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Fioricet Side Effects

Fioricet is a combination medication containing butalbital, acetaminophen, and caffeine. It’s used to treat tension headaches, but can become habit-forming. It can also worsen headaches if used too frequently, so it’s not a first-choice option for treating tension headaches.

fioricet blue and white
fioricet blue and white

Barbiturate (butalbital), acetaminophen, and caffeine analgesic combination:

  • Used to treat tension headaches in adult and pediatric patients 12 years and older; prolonged use not advisable
  • Associated with concerns of abuse, medication-overuse headache, and withdrawal; boxed warning for acetaminophen hepatotoxicity risk

Fioricet is a combination of three medications that help relieve pain caused by tension headaches (headaches that are generally related to stress and cause muscle tightness and pain around your forehead and neck).

  • Butalbital is a barbiturate that works in your brain to help you relax.
  • Acetaminophen is a pain reliever. It stops the production of certain chemicals in the brain that cause pain.
  • Caffeine is an adenosine antagonist. It blocks a natural chemical in your body called adenosine. It’s unclear exactly how caffeine works to treat headaches, but it’s thought to boost the pain-relieving activity of acetaminophen.

Butalbital APAP Caffeine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:

More common

    1. Lightheadedness
    2. shortness of breath

Incidence not known

      1. Abdominal or stomach pain
      2. black, tarry stools
      3. bleeding gums
      4. blistering, peeling, or loosening of the skin
      5. blood in the urine or stools
      6. blurred vision
      7. change in the frequency of urination or amount of urine
      8. chills
      9. cough
      10. diarrhea
      11. difficulty with breathing
      12. difficulty with swallowing
      13. dizziness
      14. drowsiness
      15. dry mouth
      16. fainting
      17. fast, pounding, or irregular heartbeat or pulse
      18. flushed or dry skin
      19. fruit-like breath odor
      20. hives, itching, or skin rash
      21. increased hunger
      22. increased thirst
      23. increased urination
      24. joint or muscle pain
      25. loss of appetite
      26. nausea or vomiting
      27. pinpoint red spots on the skin
      28. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
      29. red skin lesions, often with a purple center
      30. red, irritated eyes
      31. seizures
      32. shakiness in the legs, arms, hands, or feet
      33. sore throat
      34. sores, ulcers, or white spots in the mouth or on the lips
      35. sweating
      36. swelling of the feet or lower legs
      37. tightness in the chest
      38. trembling or shaking of the hands or feet
      39. troubled breathing
      40. unexplained weight loss
      41. unusual bleeding or bruising
      42. unusual tiredness or weakness
      43. weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

      1. Confusion as to time, place, or person
      2. dark urine
      3. difficult or painful urination
      4. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
      5. fever
      6. general feeling of discomfort or illness
      7. hallucinations
      8. headache
      9. holding false beliefs that cannot be changed by fact
      10. increased sweating
      11. irregular, fast or slow, or shallow breathing
      12. light-colored stools
      13. loss of appetite
      14. pale or blue lips, fingernails, or skin
      15. restlessness
      16. sudden decrease in the amount of urine
      17. sweating
      18. trouble sleeping
      19. unpleasant breath odor
      20. unusual excitement, nervousness, or restlessness
      21. vomiting of blood
      22. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

      1. Relaxed and calm
      2. sleepiness

Incidence not known

      1. Anxiety
      2. bloated
      3. constipation
      4. continuing ringing or buzzing or other unexplained noise in the ears
      5. depression
      6. earache
      7. excess air or gas in the stomach or intestines
      8. false or unusual sense of well-being
      9. full feeling
      10. hearing loss
      11. heartburn
      12. heavy eyelids
      13. high energy
      14. hot spells
      15. hyperventilation
      16. irritability
      17. numbness
      18. pain in the leg
      19. passing gas
      20. sluggishness
      21. stuffy nose
      22. tingling sensation

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

SIDE EFFECTS

Frequently Observed

The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.

Infrequently Observed

All adverse events tabulated below are classified as infrequent.

Central Nervous System: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of butalbital.

Autonomic Nervous System: dry mouth, hyperhidrosis.

Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation.

Cardiovascular: tachycardia.

Musculoskeletal: leg pain, muscle fatigue.

Genitourinary: diuresis.

Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions.

Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported.

The following adverse drug events may be borne in mind as potential effects of the components of this product. Potential effects of high dos age are listed in the OVERDOSAGE section.

Acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis.

Caffeine: cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia.

Drug Abuse And Dependence

Abuse And Dependee

Butalbital

Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates. The average daily dose for the barbiturate addict is usually about 1500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than two-fold. As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethal dose of a barbiturate is far less if alcohol is also ingested. Major withdrawal symptoms (convulsions anddelirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug. Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens. One method involves initiating treatment at the patient’s regular dosage level and gradually decreasing the daily dosage as tolerated by the patient.

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Fioricet is available as tablets for oral administration, to be taken whole, by mouth, with or without food. The recommended dosage is of 1-2 tablets every 4 hours or as the doctor prescribes. Fioricet treatments can cause nausea and this is why most patients prefer to take this medication without food. Talking to the doctor about the nausea problem could lead to finding out essential information on how to reduce this unwanted effect. In fact, he/she can prescribe antihistamines for the nausea but there is also the possibility of lying down one hour after taking the medication.

We do not suggest you to take Fioricet or Gabapentin for a long time, you need go to your local health professional to treat your pain without prescription. We think exercising is the best way to relieve your pain. Exercising is a very good methods. Exercising can enhance your immune system and increase your muscle strength and make your nerve strong.
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Fioricet is a combination medication commonly used to treat tension headaches but doctors also recommend it for recurring migraines. Acetaminophen is used to decrease the pain associated with muscular tension and caffeine increases the efficiency of the pain-killing effect. The last constituent of Fioricet is butalbital, a powerful sedative having the property to reduce anxiety and induce relaxation. This barbiturate is also responsible for the sleepiness appearing after Fioricet intake.

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